I like doing sequence composites and I had previously done one of this Bald Eagle fishing with 4 frames: After watching a Photoshop Week segment with Jason Hoppe on Creative Live about making animated gif files, I decided to try it out. It's pretty simplistic and crude, I know, but a fun start!
I've never tried any animation before and found it was fairly simple. I imported the 5 frames into Photoshop (I use Cs5) as layers, opened the animation frames, set the sequence and display time then in the "save for web" dialogue chose .gif and the settings I wanted. Easy peasy!